Horizant for RLS

I mentioned in my last post that I had discussed with my doctor whether Horizant is available in Thailand as I’m interested in trying it for my RLS.

Horizant is the drug Gabapentin Enacarbil (GE), which is related to an anti-seizure drug called Gabapentin (G).  I had a look online to try and find the difference, and it appears as per this review that GE has a better bioavailability than G.  What that means is that the body is able to pull more G into the bloodstream through GE rather than G.  Gabapentin has been around for many years and is available in Thailand, so my doctor asked me if I wanted to try it.  According to the study that was done on GE with RLS the dose used was 1,200 mg per day given at 5pm.  Since GE has a better bioavailability than G does that mean I need to take more G in order to get to the same level of GE?  I don’t know and I asked my doctor if she had any opinion on it.  I’m still waiting for a return email on it.

The article I reference earlier has some great info on GE and more importantly for me I found some terrific information in the extensive comments section where people actually using GE and other drugs to treat RLS talked about their experience.  Very informative.  In particular I related to this comment.

I was also surprised to find another article referenced in the comments regarding a small study suggesting that coming to orgasm before sleeping had the same effect as taking medication to treat RLS!  Wow.  RLS is so bad I’m happy to try anything that is more ‘natural’ than taking drugs.

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